MTHP – Methyl Tetra Hydro Pyran made in china CAS No. 4717-96-8 Athena 008613805212761
| CAS No. 4717-96-8 |  |
Synonym: 4-MeTHP
MTHP (4-Methyltetrahydropyran) has high polarity and high phase separation with water, as well as high stability. Therefore, it contributes to process improvements in chemical reactions, post-processing, and extraction.
- Chemical Name:
- tetrahydro-4-methyl-2H-pyran
- Synonyms
- 4-methyloxane;Einecs 225-207-5;tetrahydro–ethyl-2H-yran;4-Methyltetrahydro-2H-pyran;tetrahydro-4-methyl-2H-pyran;2H-Pyran, tetrahydro-4-methyl-;3,4,5,6-Tetrahydro-4-methyl-2H-pyran;tetrahydro-4-methyl-2H-pyran 4717-96-8;4-Methyltetrahydropyran (stabilized with BHT)
product description
Features
High Polarity
- MTHP can be used in reactions requiring polar solvents, such as organometallic reactions.
Excellent Phase Separation with Water
- MTHP allows for the entire reaction and post-processing steps to be carried out with a single solvent.
- High extraction yield.
- MTHP reduces organics in wastewater.
High Stability Against Acids, Bases, and Oxidation
- Low risk of by-product formation, contributing to the acquisition of high-purity target compounds.
Others
- Depending on the reaction and substrate, it can achieve higher reaction yields compared to other ether-based solvent systems.
- MTHP allows extremely low-temperature reactions to be carried out at milder temperatures.
- Add 15 ml of water (colored green) to each test tube.
- For the three test tubes on the right, add 15 ml of THF, 2MTHF, and MTHP (not colored) to each respective test tube.
- Shake them at room temperature for 20 seconds, then let stand for 3 hours.
＊2MTHF : 2-methyltetrahydrafuran
Applications
Reaction Solvent
- Organometallic reactions (e.g., Grignard reaction)
- Transition metal-catalyzed reactions (e.g., Suzuki-Miyaura coupling)
- Alternatives to aromatic and halogenated solvents
- Others (e.g., Azeotropic dehydration, Peptide synthesis)
Extraction Solvent
Polymerization Solvent
Coating
Physical Properties
| BP （℃） | MP （℃） | Specific gravity （20℃,g/cm3） | Viscosity（cP） | Flash point（℃） | Solubility in water（wt%） | Water solubility （wt%） |
Azeotropic point（℃）(H2O ratio) | SP value*(cal/cm3)^0.5 | |
|---|---|---|---|---|---|---|---|---|---|
| MTHP | 105 | -92 | 0.86 | 0.78 | 6.5 | 1.5 | 1.4 | 85(19wt%) | 9.0 |
| THF | 65 | -109 | 0.89 | 0.55 | -15 | ∞ | ∞ | 64(6.0wt%) | 9.5 |
| 2MTHF | 80 | -136 | 0.85 | 0.60 | -11 | 14 | 4.4 | 71(11wt%) | 8.9 |
| CPME | 106 | -140 | 0.86 | 0.55 | -1 | 1.1 | 0.3 | 83(16wt%) | 8.4 |
| Et2O | 34.6 | -116 | 0.70 | 0.24 | -45 | 6.5 | 1.2 | 34(1.3wt%) | 7.6 |
| 1,4-Dioxane | 101 | 12 | 1.04 | 1.30 | 11 | ∞ | ∞ | 88(18wt%) | 10.0 |
*Calculated according to “Hansen solubility parameters a user’s handbook 2nd edition, CRC Press, ISBN: 0-8493-7248-8”
Process improvement
MTHP can be recovered and reused due to its good separation from water. In addition, the reaction solution does not need to be concentrated or extracted during post-processing, which saves energy and reduces CO2 emissions.
Example of Process Simplification and CO2 Reduction
Superiority
What kind of chemical products do you primarily offer?
ACF Chemical Co., Ltd. have a broad product line covering fine chemicals, basic chemicals, and specialty chemicals. If you have a specific requirement, please let us know. We can provide a detailed product catalog or a customized sourcing plan.
Athena
phone/whatsapp：008613805212761
email：ceo@acfchemical.com
No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Area, China (Shandong) Pilot Free Trade Zone, 2025-3696 (A)
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Our reputation is built on stringent quality control. All our products go through a rigorous supplier vetting process and internal quality checks. We ensure that our products comply with international standards and can provide a Certificate of Analysis (COA) and other relevant documents upon request.
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We offer a variety of flexible logistics options, including sea freight, air freight, and land transport. Delivery time depends on product availability and the destination. We will provide an estimated delivery timeline upon order confirmation.
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The minimum order quantity is generally 1kg, but varies depending on the specific product. Please let us know the product you’re interested in, and our sales team will provide you with detailed information. The typical ordering process is: confirm the quote → sign the contract → pay the deposit → arrange production and shipment → pay the balance.
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| ACF Chemical Co., Ltd. Athena phone/whatsapp：008613805212761 email：ceo@acfchemical.com No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Area, China (Shandong)welcome to vist our factory. sample is free ACF Chemical Qingdao Co., Ltd. was established in 1987. the company has over decades of experience in the production of methacrylate and acrylate series products, as well as high-efficiency polymerization inhibitors and rubber and plastic antioxidant series products. The company’s leading products are high-efficiency polymerization inhibitor series products, with an annual production capacity of 1,000 tons of tert-butylhydroquinone (TBC), 800 tons of polymerization inhibitor TH-701, 500 tons of polymerization inhibitor TH-A294, 500 tons of polymerization inhibitor TH-100BE, 500 tons of phenothiazine, and 200 tons of hydroquinone. |
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