1. Pharmaceutical Intermediates

Methylamine hydrochloride is a key building block in the synthesis of a wide range of pharmaceutical compounds. It provides the methylamino group, which is essential for modifying biological activity and improving drug efficacy.

Examples of drugs synthesized using methylamine hydrochloride include:

Antihistamines

Analgesics

Antidepressants

Antihypertensive agents

Local anesthetics

Antibacterial and antifungal agents

It is used in the production of active pharmaceutical ingredients (APIs) like ephedrine, theobromine derivatives, and various sulfonamides.

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2. Agrochemicals

Methylamine hydrochloride is also used in the synthesis of pesticides, fungicides, and herbicides. It plays a role in forming methylated nitrogen-containing structures, which are crucial in designing biologically active agrochemicals.

Examples include:

Metolachlor (a widely used herbicide)

Carbamates and organophosphates that require methylamine moieties

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3. Organic Synthesis

Methylamine hydrochloride is a versatile reagent in laboratory and industrial organic chemistry. It is used for:

Reductive amination to produce secondary and tertiary amines

Amide formation

N-alkylation reactions

As a precursor for N-methylated compounds, such as methylated heterocycles and amino acids

Its solid form makes it a safer, more convenient alternative to gaseous methylamine.

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4. Polymer and Resin Manufacturing

Methylamine hydrochloride can be used in:

Crosslinking agents for resins and adhesives

Modifying polyamide or polyurethane structures

As a precursor in the manufacture of wet-strength agents for paper products

Its use enhances flexibility and adhesion in resins used for coatings, adhesives, and textiles.

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5. Dye and Pigment Synthesis

It is utilized in producing azo dyes, methylated dyes, and intermediates for pigments. The methylamino group contributes to color tuning, solubility enhancement, and light fastness.

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6. Laboratory and Analytical Reagent

Methylamine hydrochloride is a common reagent in chemical research, used for:

Preparing Schiff bases

Investigating structure–activity relationships in medicinal chemistry

Synthesis of reference compounds

Serving as a buffering agent in some analytical procedures

 

✅ Safe and Convenient Handling

Unlike the gaseous form of methylamine, the hydrochloride salt is stable, non-volatile, and easier to store and transport.

It minimizes exposure risks and simplifies procedures requiring methylamine.

✅ High Reactivity

The compound readily releases the methylamine base under mild conditions, enabling efficient amination, methylation, and condensation reactions.

✅ Versatility

Broad utility across pharmaceuticals, agrochemicals, polymers, dyes, and specialty chemicals.

Compatible with a wide range of organic reactions, including nucleophilic substitution and acid-base reactions.

✅ Water Solubility

Its high solubility in water allows for aqueous-phase synthesis and easy reaction work-up, particularly in pharma and biotech labs.

✅ Cost-Effective

Available in large volumes at competitive cost, making it suitable for both industrial-scale synthesis and R&D use.

 

 

Methylamine hydrochloride (CAS 593-51-1) is a crucial intermediate in modern chemical synthesis. From pharmaceuticals to agrochemicals, dyes to polymers, its ability to reliably introduce the methylamino group makes it an indispensable reagent. Its stability, safety profile, and wide applicability ensure its continued demand in industrial and research applications.

Superiority

What kind of chemical products do you primarily offer?
ACF Chemical Co., Ltd. have a broad product line covering fine chemicals, basic chemicals, and specialty chemicals. If you have a specific requirement, please let us know. We can provide a detailed product catalog or a customized sourcing plan.

How do you guarantee the quality and purity of your products?
Our reputation is built on stringent quality control. All our products go through a rigorous supplier vetting process and internal quality checks. We ensure that our products comply with international standards and can provide a Certificate of Analysis (COA) and other relevant documents upon request.

What are your shipping and delivery times like?

We offer a variety of flexible logistics options, including sea freight, air freight, and land transport. Delivery time depends on product availability and the destination. We will provide an estimated delivery timeline upon order confirmation.

What is the Minimum Order Quantity (MOQ)? What is the ordering process?
The minimum order quantity is generally 1kg, but varies depending on the specific product. Please let us know the product you’re interested in, and our sales team will provide you with detailed information. The typical ordering process is: confirm the quote → sign the contract → pay the deposit → arrange production and shipment → pay the balance.

Can I get technical support if I encounter issues with a product?
Absolutely. Our professional team has extensive industry knowledge and can provide support on product applications, technical parameters, and solutions. Please feel free to contact us for assistance at any time.

Can we get a sample before placing a bulk order? What payment methods do you accept?
Yes, we can usually provide samples. Depending on the product and quantity, samples may be free, but the shipping cost is typically borne by the customer. Regarding payment methods, we primarily accept T/T (Telegraphic Transfer). For long-term partners, we can discuss other flexible payment

ACF Chemical Co., Ltd. Eason     phone/whatsapp：008615252035038 email：purchase@acfchemical.com No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Area, China (Shandong)welcome to vist our factory. sample is free ACF Chemical Qingdao Co., Ltd. was established in 1987. the company has over decades of experience in the production of methacrylate and acrylate series products, as well as high-efficiency polymerization inhibitors and rubber and plastic antioxidant series products. The company’s leading products are high-efficiency polymerization inhibitor series products, with an annual production capacity of 1,000 tons of tert-butylhydroquinone (TBC), 800 tons of polymerization inhibitor TH-701, 500 tons of polymerization inhibitor TH-A294, 500 tons of polymerization inhibitor TH-100BE, 500 tons of phenothiazine, and 200 tons of hydroquinone.
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Phthallc anhydride	85-44-9
Di-tert-butyl peroxide	110-05-4
2,2,4-Trimethylpentane （ Alkylate ）	540-84-1
Tris(2-aminoethyl)amine	4097-89-6
1-HBXBnE	592-41-6
1-Octene	111-66-0
Tert-butyl cumyl peroxide	3457-61-2
n-Propyl acrylate	925-60-0
Vinyl Acetate	108-05-4
Vinyl Propionate	105-38-4
Vinyl Butyrate	123-20-6
Vinyl Caproate	3050-69-9
Vinyl Caprylate	818-44-0
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Hydrogenated Tallow Amine ethoxylate EO 20 (PEG-20 Hydrogenated Tallow Amine) – CAS: 61791-26-2	61791-26-2